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HFpEF mouse model by feeding HFD + L-NAME - left ventricle
  • Accession
    KPX10000245
  • Submission date
    2025-09-30
  • Metadata export
    XML Download
Project Detail
Dataset detail - Dataset Tilte, Species, Sample type, Disease, Offline, SCX, 16 fractions, Trypsin, Quantification, Modifications, Experiment type, MS instrument, Experimental protocol, Data analysis protocol
BioProject
 KAP241697
ProjectTitle
 Proteomic Analysis of Left Ventricular Tissue in an HFpEF Mouse Model Induced by HFD and L-NAME
Description
 This study established a cardiovascular disease model of heart failure with preserved ejection fraction (HFpEF) by feeding mice a high-fat diet (HFD) combined with L-NAME. Left ventricular tissue samples were collected for proteomic analysis. Proteomic profiling of the left ventricles at both 6 and 8 weeks revealed significant alterations in protein expression.
Keywords
  
Submitter
 Kim Jong-Seo , Seoul National University
Publication
Publication
PubMed ID DOI
   
Dataset Detail
Dataset detail - Description, Keywords, Principal investigato, Pubmed ID, Doi, Dataset Tilte, Species, Sample type, Disease, Offline, SCX, 16 fractions, Trypsin, Quantification, Modifications, Experiment type, MS instrument, Experimental protocol, Data analysis protocol
Dataset Title
 HFpEF mouse model by feeding HFD + L-NAME - left ventricle
Submission Type
 Complete
Species
 Mus musculus (Mouse)
Sample type
Sample type
Body fluid Tissue Cell Others
heart
Disease
Disease
cardiovascular system disease
Fractionation
Fractionation
Method Separation mode Number of fractions
Digestion
 Trypsin
Quantification
Quantification
Labeling Labeling Child Plex
No
Modifications
Acetyl (Protein N-term), Oxidation (M)
Modifications
Bottom-up proteomics
MS instrument
Other MS instrument - Thermofisher Scientific Orbitrap Astral Mass Spectrometer
Sample processing protocol
Data analysis protocol
Search parameters
Supplementary information
 
Announce Date
 2025-09-30
Files Summary

Total 17 files 265,652,465,475 265,652,465,475

Files Summary
File type # Files Total Size
searchResultFile 1 335,617,467 335,617,467
raw 16 265,316,848,008 265,316,848,008
File
file 목록
File Name Size Type Published Download mzMl QC file
CVD_LV_6week_HFD_1_BEH300_75u40cTI_250811.raw 16,681,829,069 16,681,829,069 2025-09-30
CVD_LV_6week_HFD_2_BEH300_75u40cTI_250811.raw 9,733,519,229 9,733,519,229 2025-09-30
CVD_LV_6week_HFD_3_BEH300_75u40cTI_250811.raw 15,456,947,165 15,456,947,165 2025-09-30
CVD_LV_6week_HFD_4_BEH300_75u40cTI_250811.raw 16,643,409,241 16,643,409,241 2025-09-30
CVD_LV_6week_HFD_LNAME_1_BEH300_75u40cTI_250811.raw 18,032,389,249 18,032,389,249 2025-09-30
CVD_LV_6week_HFD_LNAME_2_BEH300_75u40cTI_250811.raw 7,814,065,853 7,814,065,853 2025-09-30
CVD_LV_6week_HFD_LNAME_3_BEH300_75u40cTI_250811.raw 16,247,294,325 16,247,294,325 2025-09-30
CVD_LV_6week_HFD_LNAME_4_BEH300_75u40cTI_250811.raw 16,341,578,921 16,341,578,921 2025-09-30
CVD_LV_8week_HFD_1_BEH300_75u40cTI_250811.raw 19,941,655,455 19,941,655,455 2025-09-30
CVD_LV_8week_HFD_2_BEH300_75u40cTI_250811.raw 18,993,393,899 18,993,393,899 2025-09-30
CVD_LV_8week_HFD_3_BEH300_75u40cTI_250811.raw 16,825,187,671 16,825,187,671 2025-09-30
CVD_LV_8week_HFD_4_BEH300_75u40cTI_250811.raw 16,593,879,455 16,593,879,455 2025-09-30
CVD_LV_8week_HFD_LNAME_1_BEH300_75u40cTI_250811.raw 19,967,749,227 19,967,749,227 2025-09-30
CVD_LV_8week_HFD_LNAME_2_BEH300_75u40cTI_250811.raw 17,594,963,843 17,594,963,843 2025-09-30
CVD_LV_8week_HFD_LNAME_3_BEH300_75u40cTI_250811.raw 20,040,181,123 20,040,181,123 2025-09-30
CVD_LV_8week_HFD_LNAME_4_BEH300_75u40cTI_250811.raw 18,408,804,283 18,408,804,283 2025-09-30
report.parquet 335,617,467 335,617,467 parquet 2025-09-30