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BioProject Information
Project Title
Discovery and validation of prognostic biomarkers in advanced colon caner
Project Description
Due to the characteristics of clinical cancer tissue samples and limitations of analytical techniques, many of the colon cancer biomarkers reported so far have limited accuracy and consequently their clinical usefulness may be limited. In order to overcome these issues, a novel method considering various normal cells present in cancer tissues including infiltrating immune cells is applied in this study to find biomarkers with raised accuracy by analyzing transcriptome / epigenome data. Based on this approach we are planning to (1) produce colon cancer tissue sample transcriptomic / epigenomic data (n = 300), (2) Identify colorectal cancer specific epigenetic biomarkers based on blood samples and apply them to noninvasive diagnostics through clinical validation and (3) develop a diagnostic panel sequencing system for detection of epigenetic biomarkers.
Name Of Submitters Organization
Geninus Inc
Major Grant NTIS ID
-
DataType
Methyl-Seq
Data Count
130
Organism
Homo sapiens
NCBI Taxonomy ID
9606
Submission date
2025-12-16

Accession Data
BioSample
All BioSample [274]
KRA
All KRA [274]

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